Large study on older Australians (n=21,315), found that vitamin D supplementation does not significantly reduce the occurrence of major cardiovascular events.

This article discusses the effects of vitamin D supplementation on major cardiac events, based on a large randomized controlled trial, the D-Health Trial.

The trial involved 21,315 older Australians and aimed to assess the impact of monthly vitamin D supplementation (60,000 IU) on the incidence of major cardiovascular events. The study found no significant difference in the rate of major cardiovascular events between those receiving vitamin D and those receiving a placebo.

However, a few individual events showed statistically significant differences, albeit very slight. Despite these minor positive results, the trial overall adds to existing research suggesting that vitamin D supplementation offers no significant cardiovascular benefits.